Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.37 |
| ▸ | FABP7 | O15540 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2938537 | 0.82 | POLB (0.37) | HTR2AKMT2APOLBTSHRCYP1A2 | |
| SCHEMBL29129339 | 0.78 | KMT2A (0.45) | HTR2AKMT2APOLBTSHRCYP1A2 | |
| SCHEMBL5481836 | 0.75 | HTR2A (0.47) | HTR2AKMT2APOLBTSHRCYP1A2 | |
| SCHEMBL3660751 | 0.74 | KMT2A (0.43) | HTR2AKMT2APOLBTSHRCYP1A2 | |
| SCHEMBL6818503 | 0.73 | ALDH1A1 (0.42) | HTR2AKMT2APOLBTSHRCYP1A2 | |
| SCHEMBL18227243 | 0.71 | KMT2A (0.36) | HTR2AKMT2APOLBTSHRFABP5 | |
| SCHEMBL25373589 | 0.71 | ALDH1A1 (0.41) | HTR2AKMT2ATSHRCYP1A2FABP5 | |
| SCHEMBL16242267 | 0.71 | KMT2A (0.40) | HTR2AKMT2ATSHRCYP1A2FABP5 | |
| SCHEMBL5969982 | 0.71 | FABP5 (0.49) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL1639593 | 0.70 | HTR2A (0.38) | HTR2AKMT2APOLBTSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292163-A1 | Antitumoral Compounds | PHARMA MAR, S.A. (ES) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292163-A1 | Antitumoral Compounds | TP53, XPO1, TOP2B | HTR2A 4499/4885KMT2A 4262/4885POLB 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.