Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734 | 0.91 | AGTR2 (0.69) | AGTR2AGTR1 | |
| SCHEMBL1256252 | 0.89 | AGTR2 (0.66) | AGTR2AGTR1 | |
| SCHEMBL9721 | 0.88 | AGTR1 (0.85) | AGTR2AGTR1 | |
| SCHEMBL3658233 | 0.86 | GP6 (0.61) | AGTR2AGTR1 | |
| SCHEMBL3665032 | 0.84 | AGTR1 (0.57) | AGTR2AGTR1 | |
| SCHEMBL462 | 0.83 | AGTR2 (0.80) | AGTR2AGTR1 | |
| SCHEMBL7905325 | 0.83 | AGTR1 (0.58) | AGTR2AGTR1 | |
| SCHEMBL8792660 | 0.83 | AGTR2 (0.70) | AGTR2AGTR1 | |
| SCHEMBL18872571 | 0.82 | AGTR2 (0.64) | AGTR2AGTR1 | |
| SCHEMBL883 | 0.82 | AGTR1 (0.69) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146963-A2 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS | Theravance, Inc. (US) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008133896-A2 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS | THERAVANCE, INC. (US) | 2008-11-06 | — | — | WO | disclosed |