Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29867697 | 0.88 | KMT2A (0.45) | KMT2AL3MBTL1ABCB1KLK7ALDH1A1 | |
| SCHEMBL5241449 | 0.87 | ALDH1A1 (0.51) | KMT2AL3MBTL1ABCB1KLK7ALDH1A1 | |
| SCHEMBL6440981 | 0.85 | KLK7 (0.51) | KMT2AL3MBTL1KLK7ALDH1A1GAA | |
| SCHEMBL7382767 | 0.84 | FKBP1A (0.53) | KMT2AKLK7ALDH1A1GAACTSL | |
| SCHEMBL25907337 | 0.82 | ALDH1A1 (0.47) | KMT2AL3MBTL1ABCB1KLK7ALDH1A1 | |
| SCHEMBL24150906 | 0.81 | CTSL (0.52) | KMT2AL3MBTL1ABCB1KLK7ALDH1A1 | |
| SCHEMBL15955445 | 0.81 | CTSL (0.52) | KMT2AL3MBTL1ABCB1KLK7ALDH1A1 | |
| SCHEMBL17591935 | 0.81 | CTSL (0.52) | KMT2AL3MBTL1ABCB1KLK7ALDH1A1 | |
| SCHEMBL28849319 | 0.81 | CTSL (0.52) | KMT2AL3MBTL1ABCB1KLK7ALDH1A1 | |
| SCHEMBL21864768 | 0.80 | ALDH1A1 (0.52) | KMT2AL3MBTL1ABCB1KLK7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231687-A2 | NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES | Sun Pharma Advanced Research Company Limited (IN) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009116067-A2 | NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2009-09-24 | — | — | WO | disclosed |