Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12312065 | 0.84 | DRD2 (0.43) | MTNR1AMTNR1B | |
| SCHEMBL3662753 | 0.82 | SMN1; SMN2 (0.46) | MTNR1AMTNR1BKMT2ASMN1; SMN2 | |
| SCHEMBL15319511 | 0.77 | CA12 (0.56) | KMT2ASMN1; SMN2 | |
| SCHEMBL17253669 | 0.76 | ALDH1A1 (0.37) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3661730 | 0.74 | TAAR1 (0.46) | KMT2A | |
| SCHEMBL3754466 | 0.74 | L3MBTL1 (0.36) | POLBKMT2ASMN1; SMN2 | |
| SCHEMBL17221218 | 0.74 | ERN1 (0.40) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23088431 | 0.73 | L3MBTL1 (0.42) | KMT2ASMN1; SMN2 | |
| SCHEMBL17232489 | 0.72 | NQO2 (0.39) | KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25239250 | 0.72 | HTR2A (0.65) | POLBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222671-A1 | OXADIAZOLE DERIVATIVES ACTIVE ON SPHINGOSINE-1-PHOSPHATE (SIP) | Glaxo Group Limited (GB) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009080728-A1 | OXADIAZOLE DERIVATIVES ACTIVE ON SPHINGOSINE-1-PHOSPHATE (SIP) | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |