Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | USP14 | P54578 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365334 | 0.85 | L3MBTL1 (0.47) | ALDH1A1MEN1KMT2ACNR1HSD17B10 | |
| SCHEMBL366173 | 0.84 | CNR1 (0.47) | ALDH1A1MAPTMEN1HTTKMT2A | |
| SCHEMBL365029 | 0.82 | MAPT (0.50) | ALDH1A1MAPTMEN1HTTKMT2A | |
| SCHEMBL366337 | 0.82 | MAPT (0.47) | ALDH1A1MAPTMEN1HTTKMT2A | |
| SCHEMBL364926 | 0.80 | MAPT (0.49) | ALDH1A1MAPTMEN1HTTKMT2A | |
| SCHEMBL366940 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTMEN1HTTKMT2A | |
| SCHEMBL364280 | 0.78 | MAPT (0.47) | ALDH1A1MAPTMEN1HTTKMT2A | |
| SCHEMBL364338 | 0.78 | MAPT (0.47) | ALDH1A1MAPTMEN1HTTKMT2A | |
| SCHEMBL366110 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL367526 | 0.77 | MAPT (0.44) | ALDH1A1MAPTMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |