Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365335 | 0.84 | CNR2 (0.47) | CNR1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL366172 | 0.84 | ALDH1A1 (0.47) | CNR1ALDH1A1HTTMAPTMEN1 | |
| SCHEMBL365030 | 0.81 | NR4A2 (0.48) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL366338 | 0.81 | NR4A2 (0.45) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL364927 | 0.79 | SRC (0.51) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL366941 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL364339 | 0.77 | KMT2A (0.49) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL364281 | 0.77 | NR4A2 (0.48) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL367527 | 0.76 | NR4A2 (0.41) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL366111 | 0.76 | LMNA (0.52) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |