Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367332 | 0.87 | HPGD (0.50) | L3MBTL1KMT2ARAB9ACNR2HPGD | |
| SCHEMBL365228 | 0.86 | HPGD (0.47) | KMT2AMEN1RAB9ACNR2HPGD | |
| SCHEMBL366172 | 0.85 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1HSD17B10CNR1 | |
| SCHEMBL366176 | 0.83 | L3MBTL1 (0.43) | L3MBTL1KMT2AMEN1RAB9AGLA | |
| SCHEMBL364926 | 0.83 | MAPT (0.49) | L3MBTL1KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL365335 | 0.83 | CNR2 (0.47) | L3MBTL1KMT2AMEN1RAB9ACNR2 | |
| SCHEMBL366309 | 0.81 | KDM4E (0.55) | L3MBTL1KMT2AMEN1RAB9ACNR2 | |
| SCHEMBL364280 | 0.81 | MAPT (0.47) | L3MBTL1KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL364338 | 0.81 | MAPT (0.47) | L3MBTL1KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL364264 | 0.78 | MAPT (0.46) | L3MBTL1KMT2AMEN1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |