Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3007552 | 0.86 | HDAC8 (0.37) | ATMLMNAKDM4ENPSR1 | |
| SCHEMBL3005035 | 0.79 | ITGB3 (0.42) | — | |
| SCHEMBL3008460 | 0.78 | KLK5 (0.39) | — | |
| SCHEMBL3004093 | 0.68 | LMNA (0.40) | LMNAKDM4EGAARAB9A | |
| SCHEMBL31206670 | 0.66 | GLS (0.36) | LMNAKDM4EGAA | |
| SCHEMBL3004418 | 0.66 | PTGER1 (0.30) | — | |
| SCHEMBL3004413 | 0.66 | PTGER1 (0.30) | — | |
| SCHEMBL3668973 | 0.65 | CTSL (0.55) | GAA | |
| SCHEMBL3668972 | 0.65 | CTSL (0.55) | GAA | |
| SCHEMBL26970611 | 0.65 | ATM (0.43) | ATMAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152664-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | Brystol-Myers Squibb Company (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008157162-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-24 | — | — | WO | disclosed |