Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.38 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18835536 | 1.00 | RAB9A (0.44) | RAB9AKDM4ENPC1ALDH1A1L3MBTL1 | |
| SCHEMBL3662033 | 0.88 | RAB9A (0.44) | RAB9AKDM4ENPC1ALDH1A1L3MBTL1 | |
| SCHEMBL3662035 | 0.88 | RAB9A (0.44) | RAB9AKDM4ENPC1ALDH1A1L3MBTL1 | |
| SCHEMBL3595919 | 0.83 | KMT2A (0.55) | RAB9AKDM4ENPC1ALDH1A1L3MBTL1 | |
| SCHEMBL31079415 | 0.83 | KMT2A (0.55) | RAB9AKDM4ENPC1ALDH1A1L3MBTL1 | |
| SCHEMBL25706410 | 0.83 | KMT2A (0.55) | RAB9AKDM4ENPC1ALDH1A1L3MBTL1 | |
| SCHEMBL11341739 | 0.83 | PTGS2 (0.63) | RAB9AKDM4ENPC1ALDH1A1L3MBTL1 | |
| SCHEMBL11341741 | 0.83 | PTGS2 (0.63) | RAB9AKDM4ENPC1ALDH1A1L3MBTL1 | |
| SCHEMBL3595923 | 0.83 | KMT2A (0.55) | RAB9AKDM4ENPC1ALDH1A1L3MBTL1 | |
| SCHEMBL18094307 | 0.82 | ALDH1A1 (0.53) | KDM4EALDH1A1PTGS2KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137413-A1 | NOVEL HALOGEN-SUBSTITUTED COMPOUNDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137413-A1 | NOVEL HALOGEN-SUBSTITUTED COMPOUNDS | CYP4F3, PYM1, PRDX4 | RAB9A 394/4885KDM4E 1824/4885NPC1 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.