Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17258086 | 0.69 | BRD4 (0.43) | BRD4ATAD2HTR6 | |
| SCHEMBL27709898 | 0.69 | LMNA (0.44) | LMNAHPGDHTR6TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL9523688 | 0.68 | BRD4 (0.43) | BRD4ATAD2HTR6USP2 | |
| SCHEMBL15820031 | 0.68 | BRD4 (0.40) | BRD4ATAD2HTR6TAS1R3TAS1R1 | |
| SCHEMBL10752692 | 0.67 | BRD4 (0.42) | BRD4ATAD2DRD2DRD1DRD5 | |
| SCHEMBL4639207 | 0.67 | BRD4 (0.42) | BRD4ATAD2NR1H2DRD2DRD1 | |
| SCHEMBL1353797 | 0.67 | GFER (0.43) | LMNAUSP2HTT | |
| SCHEMBL3020437 | 0.67 | HTR6 (0.43) | HTR6 | |
| SCHEMBL3665960 | 0.66 | OPRD1 (0.37) | BRD4ATAD2OPRD1 | |
| SCHEMBL1440858 | 0.66 | CA12 (0.50) | LMNATAS1R3TAS1R1TAS1R2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139898-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008128961-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |