⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18105222 | 1.00 | — | — | |
| SCHEMBL1013616 | 0.77 | — | — | |
| SCHEMBL17099132 | 0.72 | — | — | |
| SCHEMBL27660434 | 0.72 | CHRNB2 (0.34) | — | |
| SCHEMBL154139 | 0.70 | — | — | |
| SCHEMBL302926 | 0.70 | — | — | |
| SCHEMBL9368994 | 0.70 | — | — | |
| SCHEMBL24725061 | 0.70 | ALDH1A1 (0.34) | — | |
| SCHEMBL12305001 | 0.69 | PTGS2 (0.40) | — | |
| SCHEMBL6558261 | 0.69 | NFE2L2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2021-08-12 | — | — | US | claimed |
| EP-4430047-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | Progentos Therapeutics, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2024144190-A1 | COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | 솔루스첨단소재 주식회사 | 2024-07-04 | — | — | WO | disclosed |
| WO-2023081923-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | Frequency Therapeutics, Inc. (US) | 2023-05-11 | — | — | WO | disclosed |
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2021-08-12 | — | — | US | disclosed |
| CN-106188043-A | Tetracyclic compound | 梅迪维新技术公司 | 2016-12-07 | — | — | CN | disclosed |
| US-9181240-B2 | Tetracyclic compounds | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-9096591-B2 | Tetracyclic compounds | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20150182509-A1 | TETRACYCLIC COMPOUNDS | MEDIVATION TECHNOLOGIES, INC. | 2015-07-02 | — | — | US | disclosed |
| US-9034880-B2 | Tetracyclic compounds | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-05-19 | — | — | US | disclosed |
| CN-102316732-A | Aza and [4,5-b] indole and methods of use | MEDIVATION TECHNOLOGIES INC | 2012-01-11 | — | — | CN | disclosed |
| CN-102227431-A | Indole and indoline derivatives and methods of use thereof | ABBOTT LAB | 2011-10-26 | — | — | CN | disclosed |
| CN-102083830-A | Pyrido [3,4-b ] indoles and methods of use | MEDIVATION TECHNOLOGIES INC | 2011-06-01 | — | — | CN | disclosed |
| CN-102046625-A | Bridged heterocyclic compounds and methods of use | MEDIVATION TECHNOLOGIES INC | 2011-05-04 | — | — | CN | disclosed |
| CN-101952284-A | Novel tetracyclic compounds | MEDIVATION TECHNOLOGIES INC | 2011-01-19 | — | — | CN | disclosed |
| EP-2217598-A1 | NEW TETRACYCLIC COMPOUNDS | Medivation Technologies, Inc. (US) | 2010-08-18 | — | — | EP | disclosed |
| US-20090239854-A1 | Tetracyclic compounds | MEDIVATION TECHNOLOGIES, INC. | 2009-09-24 | — | — | US | disclosed |
| WO-2009055828-A1 | NEW TETRACYCLIC COMPOUNDS | MEDIVATION TECHNOLOGIES, INC. (US) | 2009-04-30 | — | — | WO | disclosed |
| CN-100480340-C | Aqueous ink | TOAGOSEI CO LTD (JP) | 2009-04-22 | — | — | CN | disclosed |
| CN-1826395-A | water-soluble ink | TOAGOSEI CO LTD (JP) | 2006-08-30 | — | — | CN | disclosed |