Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 4/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144432 | 0.86 | CA1 (0.45) | MDM2TLR2TPSAB1HDAC4HDAC1 | |
| SCHEMBL366235 | 0.84 | MDM2 (0.40) | MDM2TLR2TPSAB1EPHX2SLC17A5 | |
| SCHEMBL10143499 | 0.83 | TLR2 (0.45) | MDM2TLR2TPSAB1EPHX2HDAC4 | |
| SCHEMBL10143502 | 0.82 | TLR2 (0.45) | TLR2TPSAB1HDAC4MEF2D | |
| SCHEMBL10143496 | 0.82 | CA1 (0.42) | MDM2TLR2TPSAB1HDAC4HDAC1 | |
| SCHEMBL10143500 | 0.81 | SIRT5 (0.42) | MDM2TLR2TPSAB1HDAC4HDAC1 | |
| SCHEMBL10143497 | 0.81 | TLR2 (0.42) | MDM2TLR2TPSAB1SLC17A5HDAC1 | |
| SCHEMBL10144324 | 0.80 | TLR2 (0.44) | TLR2TPSAB1HDAC4MEF2D | |
| SCHEMBL10143401 | 0.80 | TLR2 (0.46) | TLR2HDAC4HDAC1 | |
| SCHEMBL10144428 | 0.79 | TLR2 (0.42) | MDM2TLR2TPSAB1HDAC4MEF2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |