Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 5/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366234 | 0.84 | MDM2 (0.39) | MDM2TPSAB1TLR2EPHX2SLC17A5 | |
| SCHEMBL10144432 | 0.84 | CA1 (0.45) | MDM2TPSAB1TLR2 | |
| SCHEMBL10143499 | 0.84 | TLR2 (0.45) | MDM2TPSAB1TLR2EPHX2 | |
| SCHEMBL10143502 | 0.82 | TLR2 (0.45) | TPSAB1TLR2 | |
| SCHEMBL10143497 | 0.82 | TLR2 (0.42) | MDM2TPSAB1TLR2SLC17A5 | |
| SCHEMBL10143496 | 0.81 | CA1 (0.42) | MDM2TPSAB1TLR2 | |
| SCHEMBL10143401 | 0.81 | TLR2 (0.46) | TLR2 | |
| SCHEMBL10144446 | 0.80 | TLR2 (0.43) | MDM2TPSAB1TLR2EPHX2 | |
| SCHEMBL10143500 | 0.80 | SIRT5 (0.42) | MDM2TPSAB1TLR2 | |
| SCHEMBL10144324 | 0.80 | TLR2 (0.44) | TPSAB1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |