Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | TK2 | O00142 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194628 | 0.81 | KCNN4 (0.40) | MAPK1KCNN4LMNAKIF11TAAR1 | |
| SCHEMBL28893285 | 0.80 | MAPK1 (0.40) | MAPK1KCNN4LMNAKIF11TAAR1 | |
| SCHEMBL14127315 | 0.78 | KCNN4 (0.38) | MAPK1KCNN4LMNAKIF11TAAR1 | |
| SCHEMBL662477 | 0.78 | TAAR1 (0.48) | MAPK1KCNN4LMNAKIF11TAAR1 | |
| SCHEMBL663136 | 0.78 | ALDH1A1 (0.39) | MAPK1KCNN4LMNAKIF11TAAR1 | |
| SCHEMBL14269138 | 0.77 | MAPK1 (0.44) | MAPK1KCNN4KIF11TAAR1ALDH1A1 | |
| SCHEMBL4475522 | 0.76 | MAPK1 (0.36) | MAPK1KCNN4LMNAKIF11TAAR1 | |
| SCHEMBL11497301 | 0.75 | MAPK1 (0.48) | MAPK1KCNN4TAAR1ALDH1A1ALOX15 | |
| SCHEMBL15357624 | 0.74 | LMNA (0.44) | MAPK1KCNN4LMNAKIF11TAAR1 | |
| SCHEMBL11786495 | 0.74 | KIF11 (0.46) | KCNN4KIF11TAAR1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351730-B1 | ETHOXY DIPHENYL ETHANE DERIVATES, PREPARATION PROCESSES AND USES THEREOF | SHANGHAI ECUST BIOMEDICINE CO LTD (CN) | 2014-07-30 | — | — | EP | claimed |
| WO-2010043180-A1 | ETHOXY DIPHENYL ETHANE DERIVATES, PREPARATION PROCESSES AND USES THEREOF | 上海华理生物医药有限公司 (CN) | 2010-04-22 | — | — | WO | disclosed |