Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CTH | P32929 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8397576 | 0.85 | TGFBR1 (0.47) | TGFBR1EGLN1ALDH1A1KDM4ETET2 | |
| SCHEMBL65636 | 0.85 | EGLN1 (0.54) | TGFBR1EGLN1ALDH1A1KDM4ETET2 | |
| SCHEMBL27050 | 0.84 | — | — | |
| Ammonia Solution, Strong SCHEMBL18139583 | 0.83 | EGLN1 (0.52) | TGFBR1EGLN1ALDH1A1KDM4ETET2 | |
| Water SCHEMBL6572509 | 0.82 | — | — | |
| SCHEMBL15535846 | 0.82 | TGFBR1 (0.39) | TGFBR1EGLN1ALDH1A1KDM4ETET2 | |
| SCHEMBL78125 | 0.82 | TGFBR1 (0.39) | TGFBR1EGLN1ALDH1A1KDM4ETET2 | |
| Hydrochloric Acid SCHEMBL20597137 | 0.82 | — | — | |
| SCHEMBL27584868 | 0.82 | TGFBR1 (0.39) | TGFBR1EGLN1ALDH1A1KDM4ETET2 | |
| SCHEMBL15263905 | 0.81 | TGFBR1 (0.39) | TGFBR1EGLN1ALDH1A1KDM4ETET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9625617-B2 | Contact lenses comprising water soluble N-(2 hydroxyalkyl) (meth)acrylamide polymers or copolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2017-04-18 | — | — | US | claimed |
| EP-2855546-B1 | CONTACT LENSES COMPRISING WATER SOLUBLE N-(2 HYDROXYALKYL) (METH)ACRYLAMIDE POLYMERS OR COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2016-07-13 | — | — | EP | claimed |
| US-20160161639-A1 | CONTACT LENSES COMPRISING WATER SOLUBLE N-(2 HYDROXYALKYL) (METH)ACRYLAMIDE POLYMERS OR COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2016-06-09 | — | — | US | claimed |
| US-9297929-B2 | Contact lenses comprising water soluble N-(2 hydroxyalkyl) (meth)acrylamide polymers or copolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-03-29 | — | — | US | claimed |
| US-20140227482-A1 | OPTICAL LAMINATE | NITTO DENKO CORPORATION (JP) | 2014-08-14 | — | — | US | claimed |
| US-20140044891-A1 | OPTICAL LAMINATE | NITTO DENKO CORPORATION (JP) | 2014-02-13 | — | — | US | claimed |
| US-20130317132-A1 | CONTACT LENSES COMPRISING WATER SOLUBLE N-2 HYDROXYALKYL) (METH)ACRYLAMIDE POLYMERS OR COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2013-11-28 | — | — | US | claimed |
| EP-1776400-B1 | TEMPERATURE SENSITIVE POLYMERS | UNIVERSITEIT VAN UTRECHT (NL) | 2009-12-23 | — | — | EP | claimed |
| US-9720134-B2 | Optical laminate comprising hard coat layer comprised of cured product of composition comprising (meth)acrylic prepolymer having hydroxyl group | NITTO DENKO CORPORATION (JP) | 2017-08-01 | — | — | US | disclosed |
| US-9625617-B2 | Contact lenses comprising water soluble N-(2 hydroxyalkyl) (meth)acrylamide polymers or copolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2017-04-18 | — | — | US | disclosed |
| US-9625617-B2 | Contact lenses comprising water soluble N-(2 hydroxyalkyl) (meth)acrylamide polymers or copolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2017-04-18 | — | — | US | disclosed |
| US-20160161639-A1 | CONTACT LENSES COMPRISING WATER SOLUBLE N-(2 HYDROXYALKYL) (METH)ACRYLAMIDE POLYMERS OR COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2016-06-09 | — | — | US | disclosed |
| US-20160161639-A1 | CONTACT LENSES COMPRISING WATER SOLUBLE N-(2 HYDROXYALKYL) (METH)ACRYLAMIDE POLYMERS OR COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2016-06-09 | — | — | US | disclosed |
| US-9297929-B2 | Contact lenses comprising water soluble N-(2 hydroxyalkyl) (meth)acrylamide polymers or copolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-03-29 | — | — | US | disclosed |
| US-20140044891-A1 | OPTICAL LAMINATE | NITTO DENKO CORPORATION (JP) | 2014-02-13 | — | — | US | disclosed |
| US-20130317132-A1 | CONTACT LENSES COMPRISING WATER SOLUBLE N-2 HYDROXYALKYL) (METH)ACRYLAMIDE POLYMERS OR COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2013-11-28 | — | — | US | disclosed |
| US-20130317132-A1 | CONTACT LENSES COMPRISING WATER SOLUBLE N-2 HYDROXYALKYL) (METH)ACRYLAMIDE POLYMERS OR COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2013-11-28 | — | — | US | disclosed |
| WO-2013177513-A1 | CONTACT LENSES COMPRISING WATER SOLUBLE N-(2 HYDROXYALKYL) (METH)ACRYLAMIDE POLYMERS OR COPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-11-28 | — | — | WO | disclosed |
| US-8110220-B2 | Temperature sensitive polymers | UNIVERSITEIT UTRECHT (NL) | 2012-02-07 | — | — | US | disclosed |
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | UNIVERSITEIT UTRECHT (NL) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | LCT, LDHA, LDHB | TGFBR1 4012/4885EGLN1 771/4885ALDH1A1 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.