Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367733 | 0.90 | KMT2A (0.38) | KMT2AMEN1NCEH1RAB9AALDH1A1 | |
| SCHEMBL365255 | 0.87 | RAB9A (0.37) | KMT2AMEN1NCEH1RAB9AALDH1A1 | |
| SCHEMBL366611 | 0.84 | ACHE (0.38) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL366817 | 0.82 | NPC1 (0.39) | RAB9AALDH1A1 | |
| SCHEMBL367759 | 0.82 | STS (0.41) | KMT2AMEN1MKNK2ALDH1A1 | |
| SCHEMBL365836 | 0.82 | MAPT (0.38) | KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL366480 | 0.81 | ACHE (0.39) | KMT2AMEN1RAB9AALDH1A1PKM | |
| SCHEMBL366373 | 0.81 | MAPT (0.37) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL367236 | 0.81 | TSHR (0.47) | KMT2AMEN1RAB9A | |
| SCHEMBL365191 | 0.80 | MKNK2 (0.40) | KMT2AMEN1RAB9AMKNK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |