Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 7/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439962 | 0.83 | MEN1 (0.34) | PDE2AALDH1A1LMNACTSSCTSK | |
| SCHEMBL5086316 | 0.80 | ALKBH3 (0.35) | ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL26463529 | 0.76 | MCL1 (0.47) | MCL1PTPN1HSP90AA1PDE2AKIF11 | |
| SCHEMBL3411258 | 0.74 | KDM1A (0.38) | MCL1PDE2AALDH1A1CYP1A2L3MBTL1 | |
| SCHEMBL3410621 | 0.74 | NOTUM (0.46) | PDE2AKIF11CYP1A2 | |
| SCHEMBL4609341 | 0.74 | ALKBH3 (0.34) | ALDH1A1LMNA | |
| SCHEMBL3664944 | 0.73 | RAPGEF4 (0.35) | MCL1HSP90AA1HSD11B1PDK1PDK2 | |
| SCHEMBL4439261 | 0.73 | HSD11B1 (0.42) | MCL1PDE2ACTSSCTSKHSD11B1 | |
| SCHEMBL4426433 | 0.72 | HTR2B (0.36) | PDE2AALDH1A1HSD11B1 | |
| SCHEMBL19785385 | 0.70 | PDE2A (0.47) | MCL1PDE2AALDH1A1CYP1A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238133-A2 | FUNGICIDAL AMIDES | E. I. du Pont de Nemours and Company (US) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009094407-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-30 | — | — | WO | disclosed |