Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 9/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | IL2 | P60568 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437591 | 0.84 | NOTUM (0.43) | HSD11B1PDE2APDE10AGPR3 | |
| SCHEMBL4438081 | 0.82 | GPR3 (0.34) | HSD11B1GPR3 | |
| SCHEMBL4426238 | 0.79 | PDE2A (0.40) | PDE2APDE10A | |
| SCHEMBL4608929 | 0.79 | PTPN1 (0.38) | PDE2APDE10A | |
| SCHEMBL4431124 | 0.79 | ELANE (0.36) | HSD11B1EIF4E | |
| SCHEMBL19785385 | 0.78 | PDE2A (0.47) | HSD11B1PDE2AMCL1IL2CTSS | |
| SCHEMBL4428493 | 0.76 | GABRA1 (0.34) | HSD11B1PDE2APDE10A | |
| SCHEMBL9522170 | 0.75 | RORC (0.43) | KDM1A | |
| SCHEMBL6852286 | 0.75 | KMT2A (0.43) | HSD11B1 | |
| SCHEMBL3664940 | 0.73 | MCL1 (0.36) | HSD11B1PDE2AMCL1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121660-A2 | FUNGICIDAL AMIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008091580-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |