Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439963 | 0.83 | IDO1 (0.38) | RAPGEF4TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5086321 | 0.82 | ALKBH3 (0.36) | MAPTALKBH3LRRK2 | |
| SCHEMBL4609343 | 0.74 | LMNA (0.36) | ALKBH3LRRK2 | |
| SCHEMBL3664940 | 0.73 | MCL1 (0.36) | HSD11B1HSP90AA1PDK1PDK2PDK3 | |
| SCHEMBL7471001 | 0.71 | RAPGEF4 (0.37) | RAPGEF4HSD11B1IDO1NOTUM | |
| SCHEMBL3410624 | 0.71 | NOTUM (0.43) | NOTUM | |
| SCHEMBL3411260 | 0.71 | PDE2A (0.36) | IDO1 | |
| SCHEMBL167133 | 0.70 | RAPGEF4 (0.54) | RAPGEF4TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3412996 | 0.68 | ALKBH3 (0.36) | MAPTALKBH3LRRK2 | |
| SCHEMBL5086316 | 0.67 | ALKBH3 (0.35) | MAPTALKBH3LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238133-A2 | FUNGICIDAL AMIDES | E. I. du Pont de Nemours and Company (US) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009094407-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-30 | — | — | WO | disclosed |