Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940312 | 0.89 | TSHR (0.45) | TSHRMAPK1ALDH1A1KCNK3KCNK9 | |
| SCHEMBL976982 | 0.84 | KDM4E (0.50) | TSHRMAPK1ALDH1A1KDM4ETDP1 | |
| SCHEMBL3548983 | 0.83 | IRAK4 (0.53) | TSHRMAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL2366561 | 0.83 | ALDH1A1 (0.44) | TSHRMAPK1ALDH1A1KCNK3KCNK9 | |
| SCHEMBL22987944 | 0.79 | CTSD (0.57) | TSHRMAPK1ALDH1A1KCNK3KCNK9 | |
| SCHEMBL9200260 | 0.79 | PTPN1 (0.42) | TSHRMAPK1ALDH1A1KCNK3KCNK9 | |
| SCHEMBL29646310 | 0.79 | CTSD (0.57) | TSHRMAPK1ALDH1A1KCNK3KCNK9 | |
| SCHEMBL2378290 | 0.79 | YAP1 (0.40) | TSHRMAPK1ALDH1A1KCNK3KCNK9 | |
| SCHEMBL30881973 | 0.77 | TSHR (0.39) | TSHRMAPK1ALDH1A1KDM4ETDP1 | |
| SCHEMBL2164875 | 0.77 | TSHR (0.39) | TSHRMAPK1ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150113-A1 | FUNGICIDAL COMPOSITIONS | Syngeta Participations AG (CH) | 2010-02-10 | — | — | EP | claimed |
| WO-2008131901-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-11-06 | — | — | WO | claimed |