SCHEMBL3665712

SCHEMBL3665712

CN(C)Cc1ccccc1P(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 10/20 0.44
SLC6A2 P23975 8/20 0.44
ALDH1A1 P00352 2/20 0.43
TSHR P16473 2/20 0.43
CYP3A4 P08684 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
SLC6A3 Q01959 7/20 0.39
LMNA P02545 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
DRD1 P21728 2/20 0.38
HTR2A P28223 2/20 0.38
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD17B10 Q99714 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL7881740 0.98 SLC6A4 (0.43) SLC6A4SLC6A2ALDH1A1TSHRCYP3A4
Iodide SCHEMBL29883634 0.98 SLC6A4 (0.43) SLC6A4SLC6A2ALDH1A1TSHRCYP3A4
SCHEMBL24713493 0.85 ALDH1A1 (0.41) ALDH1A1CYP3A4TDP1LMNADRD1
SCHEMBL7616133 0.81 TAAR1 (0.50) CYP3A4TDP1TAAR1HTR2A
SCHEMBL7346938 0.81 TSHR (0.42) ALDH1A1TSHRCYP3A4TDP1LMNA
SCHEMBL10154135 0.79 CYP3A4 (0.39) CYP3A4TDP1TAAR1DRD1
SCHEMBL7347886 0.79 HTR1A (0.40) ALDH1A1TSHRCYP3A4TDP1LMNA
SCHEMBL19303214 0.79 KDM4E (0.42) SLC6A4SLC6A2ALDH1A1TSHRCYP3A4
SCHEMBL30090933 0.79 SIGMAR1 (0.43) SLC6A4TAAR1HTR2A
SCHEMBL15856957 0.79 CHRM2 (0.44) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3192107-B1 STABILIZED OPTICALLY ACTIVE LAYER AND METHOD FOR PRODUCTION SAMSUNG DISPLAY CO LTD (KR) 2023-08-23 EP disclosed
EP-3612544-B1 AZITHROMYCIN DERIVATIVES CONTAINING A PHOSPHONIUM ION AS ANTICANCER AGENTS RISING TIDE FOUND (CH) 2022-11-23 EP disclosed
US-11427606-B2 Azithromycin derivatives containing a phosphonium ion as anticancer agents RISING TIDE FOUND (CH) 2022-08-30 US disclosed
US-11367848-B2 Light-emitting layer suitable for bright luminescence CYNORA GMBH (DE) 2022-06-21 US disclosed
US-20210253616-A1 AZITHROMYCIN DERIVATIVES CONTAINING A PHOSPHONIUM ION AS ANTICANCER AGENTS RISING TIDE FOUND (CH) 2021-08-19 US disclosed
EP-3612544-A1 AZITHROMYCIN DERIVATIVES CONTAINING A PHOSPHONIUM ION AS ANTICANCER AGENTS Rising Tide Foundation (CH) 2020-02-26 EP disclosed
WO-2018193124-A1 AZITHROMYCIN DERIVATIVES CONTAINING A PHOSPHONIUM ION AS ANTIBACTERIAL AGENTS NOVINTUM BIOTECHNOLOGY GMBH (CH) 2018-10-25 WO disclosed
WO-2018193125-A1 AZITHROMYCIN DERIVATIVES CONTAINING A PHOSPHONIUM ION AS ANTICANCER AGENTS NOVINTUM BIOTECHNOLOGY GMBH (CH) 2018-10-25 WO disclosed
EP-2938618-B1 BINUCLEAR METAL(I) COMPLEXES FOR USE IN OPTOELECTRONICS CYNORA GMBH (DE) 2017-11-15 EP disclosed
US-20170250363-A1 LIGHT-EMITTING LAYER SUITABLE FOR BRIGHT LUMINESCENCE CYNORA GMBH (DE) 2017-08-31 US disclosed
US-20150340614-A1 BINUCLEAR METAL(I) COMPLEXES FOR OPTOELECTRONIC APPLICATIONS CYNORA GMBH (DE) 2015-11-26 US disclosed
WO-2014102079-A1 BINUCLEAR METAL(I) COMPLEXES FOR OPTOELECTRONIC APPLICATIONS CYNORA GMBH (DE) 2014-07-03 WO disclosed
EP-2749563-A1 Binuclear metal(I) complexes for use in optoelectronics cynora GmbH (DE) 2014-07-02 EP disclosed
EP-2231570-A1 RHODIUM-PHOSPHORUS COMPLEXES AND THEIR USE IN RING OPENING REACTIONS Laboratorios del Dr. Esteve S.A. (ES) 2010-09-29 EP disclosed
WO-2009074496-A1 RHODIUM-PHOSPHORUS COMPLEXES AND THEIR USE IN RING OPENING REACTIONS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2009-06-18 WO disclosed
EP-0307026-B1 PROCESS FOR THE PREPARATION OF A BUTENE SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-03-18 EP disclosed
EP-0259914-B1 NOVEL CATALYST COMPOSITIONS AND PROCESS FOR OLEFIN/CO COPOLYMERIZATION SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-03-04 EP disclosed
US-4892885-A CARDIOTONICS, DIURETICS AMERICAN CYANAMID COMPANY 1990-01-09 US disclosed
EP-0307026-A1 Process for the preparation of a butene SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-03-15 EP disclosed
EP-0259914-A1 Novel catalyst compositions and process for olefin/CO copolymerization SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11427606-B2 Azithromycin derivatives containing a phosphonium ion as anticancer agents PHPT1, NUP205, PIK3CA SLC6A4 2731/4885SLC6A2 4208/4885ALDH1A1 4620/4885
US-20150340614-A1 BINUCLEAR METAL(I) COMPLEXES FOR OPTOELECTRONIC APPLICATIONS OCIAD2, OCIAD1, CRY2 SLC6A4 3895/4885SLC6A2 2682/4885ALDH1A1 2048/4885
US-20210253616-A1 AZITHROMYCIN DERIVATIVES CONTAINING A PHOSPHONIUM ION AS ANTICANCER AGENTS PHPT1, NUP205, PIK3CA SLC6A4 2731/4885SLC6A2 4208/4885ALDH1A1 4620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.