SCHEMBL3665950

SCHEMBL3665950

C=C(C)C(=O)OC(CC)C([SiH3])(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
TSHR P16473 3/20 0.34
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3971381 0.87 ALDH1A1 (0.34) THRBTSHRALDH1A1
SCHEMBL584058 0.85 ALDH1A1 (0.38) THRBTSHRALDH1A1
SCHEMBL758665 0.81 TSHR (0.33) THRBTSHRALDH1A1
SCHEMBL7025018 0.79 TSHR (0.36) THRBTSHRALDH1A1
SCHEMBL28916320 0.78 TSHR (0.35) THRBTSHRALDH1A1
SCHEMBL23494391 0.77 TSHR (0.39) THRBTSHRALDH1A1
SCHEMBL27278549 0.77 TSHR (0.39) THRBTSHRALDH1A1
SCHEMBL10430814 0.77 THRB (0.36) THRBTSHRALDH1A1
SCHEMBL8416409 0.76 TSHR (0.46) THRBTSHRALDH1A1
SCHEMBL3478201 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2217661-A2 IMPACT RESISTANT, FLAME RETARDANT THERMOPLASTIC MOLDING COMPOSITION Bayer MaterialScience LLC (US) 2010-08-18 EP disclosed
US-7595352-B2 Photo-curable adhesive composition, optical pick-up device using the same, and optical recording/reproducing drive including the optical pick-up device SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-09-29 US disclosed
WO-2009105087-A2 IMPACT RESISTANT, FLAME RETARDANT THERMOPLASTIC MOLDING COMPOSITION BAYER MATERIAL SCIENCE LLC (US) 2009-08-27 WO disclosed
US-20070054975-A1 Photo-curable adhesive composition, optical pick-up device using the same, and optical recording/reproducing drive including the optical pick-up device SAMSUNG ELECTRONICS CO., LTD. 2007-03-08 US disclosed
EP-1394217-A2 Polymeric compositions useful in plastic resins ROHM AND HAAS COMPANY (US) 2004-03-03 EP disclosed
EP-1394209-A1 Polymeric compositions useful in plastic resins ROHM AND HAAS COMPANY (US) 2004-03-03 EP disclosed
US-5196260-A Polysiloxanes with vinyl groups copolymerized with vinyl monomer, washfastness, whiteness CIBA-GEIGY CORPORATION (US) 1993-03-23 US disclosed
EP-0308871-A2 Thermoplastic polyester resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-03-29 EP disclosed