SCHEMBL28916320

SCHEMBL28916320

C=CC(=O)OC(CC)C([SiH3])(OCC)OCC

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
HPGD P15428 1/20 0.34
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26124894 0.87 TSHR (0.36) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL584641 0.84 TSHR (0.36) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL3665950 0.78 THRB (0.36) TSHRTHRBALDH1A1
SCHEMBL3478326 0.78 TSHR (0.32) TSHRHPGD
SCHEMBL6782736 0.76 TSHR (0.41) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL17300322 0.74 TSHR (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL28170370 0.74 THRB (0.40) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL109234 0.74 TSHR (0.36) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL23494166 0.73 THRB (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL28873659 0.73 TSHR (0.42) TSHRHPGDTHRBALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250019536-A1 STRESS REDUCING AGENT AND RESIN COMPOSITION KANEKA CORPORATION (JP) 2025-01-16 US disclosed
US-20250011596-A1 SILICONE CORE ACRYLIC SHELL IMPACT MODIFIERS CONTAINING PHOSPHORUS ROHM & HAAS (US) 2025-01-09 US disclosed
EP-4444774-A1 SILICONE CORE ACRYLIC SHELL IMPACT MODIFIERS CONTAINING PHOSPHORUS Rohm and Haas Company (US) 2024-10-16 EP disclosed
EP-4446352-A1 WATER-BASED COATING Kaneka Corporation (JP) 2024-10-16 EP disclosed
US-20240327671-A1 WATER-BASED COATING KANEKA CORPORATION (JP) 2024-10-03 US disclosed
WO-2023107523-A1 SILICONE CORE ACRYLIC SHELL IMPACT MODIFIERS CONTAINING PHOSPHORUS ROHM AND HAAS COMPANY (US) 2023-06-15 WO disclosed
WO-2023106317-A1 WATER-BASED COATING 株式会社カネカ 2023-06-15 WO disclosed
CN-110536932-B Polyorganosiloxane-containing rubber latex, process for producing the same, and polyorganosiloxane-containing rubber graft polymer 三菱化学株式会社 2022-12-23 CN disclosed
US-11292771-B2 Amidine catalyst for curable compositions SIKA TECHNOLOGY AG (CH) 2022-04-05 US disclosed
EP-3392036-B1 METHOD FOR PRODUCING LAMINATE, AND LAMINATE KANEKA CORP (JP) 2022-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11292771-B2 Amidine catalyst for curable compositions ADM2, GMNN, ARG1 TSHR 4780/4885HPGD 3382/4885THRB 4821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.