SCHEMBL366630

SCHEMBL366630

C=C=C(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.41
CES2 O00748 2/20 0.41
TSHR P16473 2/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
ALDH1A1 P00352 1/20 0.41
POLB P06746 2/20 0.39
AKT1 P31749 1/20 0.39
F2 P00734 2/20 0.38
CYP3A4 P08684 2/20 0.38
MAPT P10636 2/20 0.38
BLM P54132 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
CA2 P00918 2/20 0.38
CA4 P22748 2/20 0.38
F10 P00742 1/20 0.38
F12 P00748 1/20 0.38
F7 P08709 1/20 0.38
F3 P13726 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6935566 0.78 CES1 (0.38) CES1CES2TSHRDAONAPRT
SCHEMBL18428678 0.77 CA2 (0.42) CES1CES2TSHRDAONAPRT
SCHEMBL7136968 0.75 CES1 (0.45) CES1CES2TSHRDAONAPRT
SCHEMBL2181511 0.75 ALDH1A1 (0.53) CES1CES2TSHRDAONAPRT
SCHEMBL2698765 0.74 CES1 (0.39) CES1CES2TSHRDAONAPRT
SCHEMBL10594203 0.74 MAPT (0.50) CES2TSHRALDH1A1CYP3A4MAPT
SCHEMBL24527556 0.72 CES1 (0.38) CES1CES2TSHRDAONAPRT
SCHEMBL6119229 0.72 CES1 (0.38) CES1CES2TSHRDAONAPRT
SCHEMBL645042 0.72 CES1 (0.50) CES1CES2TSHRDAONAPRT
SCHEMBL2458795 0.72 CES2 (0.42) CES1CES2TSHRDAONAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5428111-A Block polymers UNIVERSITY OF MASSACHUSETTS (US) 1995-06-27 US claimed
EP-0141612-B1 CURABLE BISIMIDE RESIN MIXTURES Technochemie GmbH - Verfahrenstechnik (DE) 1990-04-11 EP claimed
US-4898941-A Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-02-06 US claimed
US-4892973-A FROM CORRESPONDING ALKANE BY OXIDATION WITH LEAD PEROXIDE YAMADA CHEMICAL CO., LTD. (JP) 1990-01-09 US claimed
US-4806419-A HEAT RESISTANCE, IMPACT STRENGTH THE BOOTS COMPANY PLC (GB) 1989-02-21 US claimed
EP-0257591-A2 Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-03-02 EP claimed
EP-0141612-A2 Curable Bisimide Resin Mixtures Technochemie GmbH - Verfahrenstechnik (DE) 1985-05-15 EP claimed
JP-3083985-A None JP disclosed
JP-62202787-A None JP disclosed
JP-62170387-A None JP disclosed
US-20240182640-A1 Resin Composition, Molded Body, And Their Application MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-06-06 US disclosed
CN-117924713-A Diphenyl polyether modified organic silicon and preparation method and application thereof 江西三越高分子材料有限公司 2024-04-26 CN disclosed
CN-112739779-B Resin composition, molded article, and use thereof 三菱瓦斯化学株式会社 2023-02-21 CN disclosed
US-4556677-A ESTROGENIC, ANTIESTROGENIC, PROGESTANIC, ANTITUMOR AGENTS FARMOS GROUP LTD. (FI) 1985-12-03 US disclosed
EP-0141612-A2 Curable Bisimide Resin Mixtures Technochemie GmbH - Verfahrenstechnik (DE) 1985-05-15 EP disclosed
EP-0078158-A2 Novel alkane and alkene derivatives and their preparation and use Farmos Group Ltd. (FI) 1983-05-04 EP disclosed
EP-0066943-A1 1,1-Diphenylalkenes and a process for their preparation IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-12-15 EP disclosed
US-4073876-A Preparation of glycol esters HALCON INTERNATIONAL, INC. (US) 1978-02-14 US disclosed
US-4045477-A HYDROXYESTERS FROM OXIDATION OF OLEFINS IN A CARBOXYLIC ACID WITH A TELLURIUM IODINE SOURCE CATALYST CHEM SYSTEMS INC. (US) 1977-08-30 US disclosed
US-3985795-A Process for preparing glycols from their ester precursors HALCON INTERNATIONAL, INC. (US) 1976-10-12 US disclosed