Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 7/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16238007 | 1.00 | GSR (0.45) | GSRCA2MEN1KMT2ASLC18A3 | |
| SCHEMBL19551024 | 1.00 | GSR (0.45) | GSRCA2MEN1KMT2ASLC18A3 | |
| SCHEMBL19551025 | 1.00 | GSR (0.45) | GSRCA2MEN1KMT2ASLC18A3 | |
| SCHEMBL16254272 | 1.00 | GSR (0.45) | GSRCA2MEN1KMT2ASLC18A3 | |
| SCHEMBL6900128 | 0.84 | CA1 (0.44) | GSRCA2CA1CA4 | |
| Nitric Acid SCHEMBL9874582 | 0.72 | GSR (0.54) | GSRCA2MEN1KMT2ASLC18A3 | |
| Nitric Acid SCHEMBL9803591 | 0.72 | GSR (0.54) | GSRCA2MEN1KMT2ASLC18A3 | |
| SCHEMBL12723211 | 0.72 | — | — | |
| SCHEMBL23515650 | 0.72 | MAPT (0.34) | GSRCA2 | |
| SCHEMBL21054688 | 0.72 | MAPT (0.34) | GSRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234987-B1 | PERHYDROQUINOXALINE DERIVATIVES AS ANALGESICS | WOLFF AUGUST GMBH & CO KG ARZNEIMITTEL DR (DE) | 2012-12-12 | — | — | EP | claimed |
| US-8309725-B2 | Perhydroquinoxaline derivatives, their preparation and use in medicaments | Dr. August Wolff GmbH & Co. KG—Arzneimittel (DE) | 2012-11-13 | — | — | US | claimed |
| EP-2234987-A2 | PERHYDROQUINOXALINE DERIVATIVES AS ANALGESICS | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2010-10-06 | — | — | EP | claimed |
| WO-2009080745-A2 | PERHYDROQUINOXALINE DERIVATIVES | Westfälische Wilhelms Universität Münster (DE) | 2009-07-02 | — | — | WO | claimed |
| US-20160122307-A1 | PERHYDROQUINOXALINE DERIVATIVES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2016-05-05 | — | — | US | disclosed |
| EP-2997025-A1 | PERHYDROQUINOXALINE DERIVATIVES USEFUL AS ANALGESICS | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184355-A1 | PERHYDROQUINOXALINE DERIVATIVES USEFUL AS ANALGESICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2014-11-20 | — | — | WO | disclosed |
| EP-2234987-B1 | PERHYDROQUINOXALINE DERIVATIVES AS ANALGESICS | WOLFF AUGUST GMBH & CO KG ARZNEIMITTEL DR (DE) | 2012-12-12 | — | — | EP | disclosed |
| US-8309725-B2 | Perhydroquinoxaline derivatives, their preparation and use in medicaments | Dr. August Wolff GmbH & Co. KG—Arzneimittel (DE) | 2012-11-13 | — | — | US | disclosed |
| US-20100311761-A1 | PERHYDROQUINOXALINE DERIVATIVES | DR. AUGUST WOLFF GMBH & CO. KG - ARZNEIMITTEL (DE) | 2010-12-09 | — | — | US | disclosed |
| EP-2234987-A2 | PERHYDROQUINOXALINE DERIVATIVES AS ANALGESICS | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009080745-A2 | PERHYDROQUINOXALINE DERIVATIVES | Westfälische Wilhelms Universität Münster (DE) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122307-A1 | PERHYDROQUINOXALINE DERIVATIVES | PTGS1, HPGD, HMOX1 | GSR 120/4885CA2 1392/4885MEN1 3821/4885 |
| US-20100311761-A1 | PERHYDROQUINOXALINE DERIVATIVES | FH, HOGA1, SDHA | GSR 60/4885CA2 2010/4885MEN1 1827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.