Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.57 |
| ▸ | P4HB | P07237 | 5/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Wr-190433 SCHEMBL29870441 | 0.84 | TUBB4A (0.66) | HSP90AA1KDM4EMAPTCYP1B1ALDH1A1 | |
| Wr-190433 SCHEMBL6180067 | 0.84 | TUBB4A (0.66) | HSP90AA1KDM4EMAPTCYP1B1ALDH1A1 | |
| Wr-190433 SCHEMBL30880222 | 0.84 | TUBB4A (0.66) | HSP90AA1KDM4EMAPTCYP1B1ALDH1A1 | |
| Wr-190433 SCHEMBL977482 | 0.84 | TUBB4A (0.66) | HSP90AA1KDM4EMAPTCYP1B1ALDH1A1 | |
| SCHEMBL10376864 | 0.84 | MAPT (0.63) | HSP90AA1P4HBKDM4EMAPTCYP1B1 | |
| SCHEMBL10376866 | 0.84 | MAPT (0.63) | HSP90AA1P4HBKDM4EMAPTCYP1B1 | |
| SCHEMBL1604279 | 0.83 | TUBB4A (0.65) | HSP90AA1P4HBKDM4EMAPTCYP1B1 | |
| SCHEMBL28713225 | 0.83 | TUBB4A (0.65) | HSP90AA1P4HBKDM4EMAPTCYP1B1 | |
| SCHEMBL15882451 | 0.82 | TUBB4A (0.72) | HSP90AA1KDM4EMAPTCYP1B1ALDH1A1 | |
| SCHEMBL15882450 | 0.82 | TUBB4A (0.72) | HSP90AA1KDM4EMAPTCYP1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242742-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2015-12-02 | — | — | EP | disclosed |
| US-8343966-B2 | Organic compounds | NOVARTIS AG (CH) | 2013-01-01 | — | — | US | disclosed |
| EP-2242742-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2010-10-27 | — | — | EP | disclosed |
| US-20090215776-A1 | Organic compounds | ADCOCK CLAIRE | 2009-08-27 | — | — | US | disclosed |
| WO-2009087212-A2 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215776-A1 | Organic compounds | REN, RXFP1, MYLK | USP2 3412/4885HSP90AA1 4151/4885P4HB 3076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.