Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296451 | 0.68 | F10 (0.72) | F10F2 | |
| SCHEMBL296450 | 0.68 | F10 (0.72) | F10F2 | |
| SCHEMBL157569 | 0.68 | F10 (0.47) | F10KMT2AMEN1MAPTNPC1 | |
| SCHEMBL12503549 | 0.66 | F10 (0.55) | F10MAPTNPC1RAB9AKDM4E | |
| SCHEMBL891013 | 0.65 | GPR35 (0.40) | F10KMT2AMEN1MAPTNPC1 | |
| SCHEMBL5419665 | 0.61 | F10 (0.74) | F10KMT2AMEN1MAPTNPC1 | |
| SCHEMBL16353402 | 0.60 | G6PC1 (0.56) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL7250878 | 0.59 | F10 (1.00) | F10KMT2AMEN1MAPTNPC1 | |
| SCHEMBL31680510 | 0.58 | SMN1; SMN2 (0.88) | F10KMT2AMEN1MAPTNPC1 | |
| SCHEMBL7244178 | 0.58 | F10 (0.73) | F10KMT2AMEN1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155195-A2 | COMBINATION ANTICOAGULANT THERAPY WITH A COMPOUND THAT ACTS AS A FACTOR XA INHIBITOR | Millennium Pharmaceuticals, Inc. (US) | 2010-02-24 | — | — | EP | claimed |
| WO-2008127682-A2 | COMBINATION ANTICOAGULANT THERAPY WITH A COMPOUND THAT ACTS AS A FACTOR XA INHIBITOR | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-10-23 | — | — | WO | claimed |