Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | CCR6 | P51684 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365146 | 0.90 | IDO1 (0.40) | KDM4EMEN1ALDH1A1KMT2AAPAF1 | |
| SCHEMBL364652 | 0.83 | CA2 (0.40) | KDM4EMEN1ALDH1A1KMT2AAPAF1 | |
| SCHEMBL367706 | 0.82 | BAZ2B (0.41) | KDM4EMEN1ALDH1A1KMT2AAPAF1 | |
| SCHEMBL366741 | 0.80 | EGFR (0.38) | MEN1KMT2AKCNH2HTR2AHTR2C | |
| SCHEMBL366998 | 0.80 | HTT (0.46) | KDM4EMEN1ALDH1A1KMT2AAPAF1 | |
| SCHEMBL366925 | 0.78 | ALDH1A1 (0.55) | KDM4EMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL367763 | 0.77 | BAZ2B (0.45) | KDM4EMEN1ALDH1A1KMT2AAPAF1 | |
| SCHEMBL367200 | 0.76 | KDM4E (0.55) | KDM4EMEN1ALDH1A1KMT2AAPAF1 | |
| SCHEMBL365647 | 0.74 | IDO1 (0.43) | KDM4EMEN1ALDH1A1KMT2AAPAF1 | |
| SCHEMBL365258 | 0.74 | KDM4E (0.42) | KDM4EMEN1ALDH1A1KMT2AAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |