SCHEMBL3667480

SCHEMBL3667480

CC1=Cc2cccc(-n3c4ccccc4c4ccccc43)c2C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 2/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HTT P42858 2/20 0.34
MAPT P10636 2/20 0.34
LMNA P02545 1/20 0.34
ALKBH5 Q6P6C2 1/20 0.33
FTO Q9C0B1 1/20 0.33
GPR3 P46089 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
POLB P06746 1/20 0.33
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
HPGD P15428 2/20 0.31
HSD17B10 Q99714 2/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL830800 0.76 ALDH1A1 (0.39) ALDH1A1KDM4EATML3MBTL1HTT
SCHEMBL3690934 0.75 BIRC5 (0.36) ALDH1A1MAPT
SCHEMBL3687303 0.73 CYP1A2 (0.39) ALDH1A1KDM4EMAPTLMNAGAA
SCHEMBL17994952 0.72 ACHE (0.43) ALDH1A1KDM4EATML3MBTL1ALKBH5
SCHEMBL10029971 0.72 ALDH1A1 (0.50) ALDH1A1KDM4EATML3MBTL1HTT
SCHEMBL5602633 0.71 MAOA (0.41) ALDH1A1HTTBCHEACHECYP2C19
SCHEMBL14557135 0.69 ALDH1A1 (0.55) ALDH1A1KDM4EATML3MBTL1HTT
SCHEMBL546098 0.69 ALDH1A1 (0.59) ALDH1A1KDM4EATML3MBTL1HTT
SCHEMBL30572834 0.69 ALDH1A1 (0.59) ALDH1A1KDM4EATML3MBTL1HTT
SCHEMBL26536918 0.68 ALDH1A1 (0.47) ALDH1A1KDM4EATML3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2240520-B1 PRODUCTION OF PROPYLENE-BASED POLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-04-24 EP disclosed
EP-2240520-A2 PRODUCTION OF PROPYLENE-BASED POLYMERS ExxonMobil Chemical Patents Inc. (US) 2010-10-20 EP disclosed
US-7812104-B2 Production of propylene-based polymers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-10-12 US disclosed
US-7812104-B2 Production of propylene-based polymers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-10-12 US disclosed
EP-2103634-A1 Production of propylene-based polymers ExxonMobil Chemical Patents Inc. (US) 2009-09-23 EP disclosed
US-20090186995-A1 Production of Propylene-Based Polymers EXXONMOBIL CHEMICAL PATENTS INC. 2009-07-23 US disclosed
US-20090186995-A1 Production of Propylene-Based Polymers EXXONMOBIL CHEMICAL PATENTS INC. 2009-07-23 US disclosed
WO-2009091480-A2 PRODUCTION OF PROPYLENE-BASED POLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-07-23 WO disclosed