SCHEMBL3687303

SCHEMBL3687303

CC1=Cc2cccc(-n3cccc3)c2C1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
MAPK1 P28482 1/20 0.34
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3667480 0.73 ALDH1A1 (0.38) CYP2C19ALDH1A1MAPTKDM4EGAA
SCHEMBL3690934 0.73 BIRC5 (0.36) ALDH1A1MAPT
SCHEMBL3679500 0.73 CYP1A2 (0.40) CYP1A2CYP2C19ALDH1A1MAPTKDM4E
SCHEMBL5953457 0.72 CYP2A6 (0.35) CYP1A2ALDH1A1
SCHEMBL30667121 0.72 CYP2A6 (0.35) CYP1A2ALDH1A1
SCHEMBL5602633 0.72 MAOA (0.41) CYP1A2CYP2C19ALDH1A1
SCHEMBL18033909 0.70
SCHEMBL1319720 0.69 TRPA1 (0.41) ALDH1A1
SCHEMBL12122310 0.69
SCHEMBL1452615 0.69 ADRA2A (0.36) CYP1A2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2240520-B1 PRODUCTION OF PROPYLENE-BASED POLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-04-24 EP disclosed
EP-2240520-A2 PRODUCTION OF PROPYLENE-BASED POLYMERS ExxonMobil Chemical Patents Inc. (US) 2010-10-20 EP disclosed
US-7812104-B2 Production of propylene-based polymers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-10-12 US disclosed
US-7812104-B2 Production of propylene-based polymers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-10-12 US disclosed
EP-2103634-A1 Production of propylene-based polymers ExxonMobil Chemical Patents Inc. (US) 2009-09-23 EP disclosed
US-20090186995-A1 Production of Propylene-Based Polymers EXXONMOBIL CHEMICAL PATENTS INC. 2009-07-23 US disclosed
US-20090186995-A1 Production of Propylene-Based Polymers EXXONMOBIL CHEMICAL PATENTS INC. 2009-07-23 US disclosed
WO-2009091480-A2 PRODUCTION OF PROPYLENE-BASED POLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-07-23 WO disclosed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO disclosed