Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364770 | 0.88 | ELANE (0.48) | LMNACYP1A2CYP2C19MAPK1CYP2D6 | |
| SCHEMBL365894 | 0.86 | TSHR (0.48) | TSHRL3MBTL1TDP1EGFRLMNA | |
| SCHEMBL366765 | 0.82 | TSHR (0.48) | TSHRL3MBTL1TDP1EGFRLMNA | |
| SCHEMBL366753 | 0.82 | KMT2A (0.52) | TSHRL3MBTL1TDP1EGFRLMNA | |
| SCHEMBL365762 | 0.81 | ALDH1A1 (0.44) | L3MBTL1TDP1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL364281 | 0.81 | NR4A2 (0.48) | EGFRLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL366000 | 0.80 | ELANE (0.47) | TSHRTDP1LMNAESR1ALDH1A1 | |
| SCHEMBL367569 | 0.79 | SRC (0.46) | EGFRLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL366763 | 0.79 | ALDH1A1 (0.44) | TSHRL3MBTL1TDP1EGFRLMNA | |
| SCHEMBL367540 | 0.79 | PSEN1 (0.45) | TSHRL3MBTL1TDP1EGFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |