Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365549 | 0.88 | ALDH1A1 (0.47) | ELANELMNAHTTALDH1A1TDP1 | |
| SCHEMBL367091 | 0.85 | KMT2A (0.44) | ELANELMNAHTTALDH1A1NR4A2 | |
| SCHEMBL365999 | 0.83 | ALDH1A1 (0.48) | ELANELMNAGABRPGABRDGABRA1 | |
| SCHEMBL365400 | 0.81 | ELANE (0.47) | ELANELMNAGABRPGABRDGABRA1 | |
| SCHEMBL366754 | 0.80 | TSHR (0.45) | ELANELMNAALDH1A1ESR1TSHR | |
| SCHEMBL365912 | 0.80 | CES1 (0.45) | HTTALDH1A1 | |
| SCHEMBL365635 | 0.78 | IDO1 (0.44) | ELANELMNAHTTALDH1A1 | |
| SCHEMBL367044 | 0.78 | ELANE (0.39) | ELANELMNAGABRPGABRDGABRA1 | |
| SCHEMBL364770 | 0.76 | ELANE (0.48) | ELANELMNAALDH1A1F2PLAU | |
| SCHEMBL366312 | 0.76 | ALDH1A1 (0.52) | LMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |