Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954537 | 0.75 | ALDH1A1 (0.30) | — | |
| SCHEMBL4232939 | 0.75 | — | — | |
| SCHEMBL177657 | 0.73 | — | — | |
| SCHEMBL6950949 | 0.69 | — | — | |
| SCHEMBL13905725 | 0.68 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL15925489 | 0.65 | — | — | |
| SCHEMBL8855266 | 0.63 | — | — | |
| SCHEMBL31546156 | 0.63 | — | — | |
| SCHEMBL9533994 | 0.63 | — | — | |
| SCHEMBL11792751 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108646-B1 | Alpha, Alpha'-Dihydroxyketone derivatives and their use as UV filters | MERCK PATENT GMBH (DE) | 2010-10-27 | — | — | EP | claimed |
| EP-2108646-A1 | Alpha, Alpha'-Dihydroxyketone derivatives and their use as UV filters | Merck Patent GmbH (DE) | 2009-10-14 | — | — | EP | claimed |
| EP-2673267-B1 | 1,3-DIOXAN-5-ONE COMPOUNDS | MERCK PATENT GMBH (DE) | 2015-06-03 | — | — | EP | disclosed |
| EP-2673267-B1 | 1,3-DIOXAN-5-ONE COMPOUNDS | MERCK PATENT GMBH (DE) | 2015-06-03 | — | — | EP | disclosed |
| EP-2673267-A1 | 1,3-DIOXAN-5-ONE COMPOUNDS | Merck Patent GmbH (DE) | 2013-12-18 | — | — | EP | disclosed |
| US-20130309184-A1 | 1,3-DIOXAN-5-ONE COMPOUNDS | MERCK PATENT GMBH (DE) | 2013-11-21 | — | — | US | disclosed |
| US-20130309184-A1 | 1,3-DIOXAN-5-ONE COMPOUNDS | MERCK PATENT GMBH (DE) | 2013-11-21 | — | — | US | disclosed |
| WO-2012107158-A1 | 1,3-DIOXAN-5-ONE COMPOUNDS | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |
| EP-2108646-B1 | Alpha, Alpha'-Dihydroxyketone derivatives and their use as UV filters | MERCK PATENT GMBH (DE) | 2010-10-27 | — | — | EP | disclosed |
| EP-2108646-B1 | Alpha, Alpha'-Dihydroxyketone derivatives and their use as UV filters | MERCK PATENT GMBH (DE) | 2010-10-27 | — | — | EP | disclosed |
| EP-2108646-A1 | Alpha, Alpha'-Dihydroxyketone derivatives and their use as UV filters | Merck Patent GmbH (DE) | 2009-10-14 | — | — | EP | disclosed |
| WO-2009030372-A1 | BI-FUNCTIONAL DHA DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-03-12 | — | — | WO | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| EP-1934188-A2 | ALPHA, ALPHA`-DIHYDROXY KETONE DERIVATIVES AND USE THEREOF AS UV FILTER | Merck Patent GmbH (DE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007039110-A2 | α, α′-DIHYDROXY KETONE DERIVATIVES AND USE THEREOF AS UV FILTER | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039110-A2 | α, α′-DIHYDROXY KETONE DERIVATIVES AND USE THEREOF AS UV FILTER | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |
| US-20040214819-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2004-10-28 | — | — | US | disclosed |
| US-20030069231-A1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | RUDOLF KLAUS (DE) | 2003-04-10 | — | — | US | disclosed |
| US-6344449-B1 | HEADACHE AND MORPHINE DEPENDENCE | DR. KARL THOMAE GMBH (DE) | 2002-02-05 | — | — | US | disclosed |
| US-20010036946-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | RUDOLF KLAUS (DE) | 2001-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214819-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, SRMS, OPRM1 | CA1 714/4885CA9 1365/4885 |
| US-20030069231-A1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | SLC1A5, NEFM, SRMS | CA1 655/4885CA9 1191/4885 |
| US-20130309184-A1 | 1,3-DIOXAN-5-ONE COMPOUNDS | AOX1, OCIAD1, OCIAD2 | CA1 3014/4885CA9 2456/4885 |
| US-20010036946-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, SRMS, OPRM1 | CA1 714/4885CA9 1365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.