SCHEMBL3668079

SCHEMBL3668079

O=C1N[C@@H]2CCN(C(=O)O)C12

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3608557 1.00 L3MBTL1 (0.33) L3MBTL1RIPK1
SCHEMBL1687128 0.79 FHIT (0.30)
SCHEMBL5135065 0.79 FHIT (0.30)
SCHEMBL5135069 0.79 FHIT (0.30)
SCHEMBL7191837 0.75 NPC1 (0.50)
SCHEMBL2216944 0.75 KDM4E (0.40)
SCHEMBL7197551 0.74 ROCK2 (0.38)
SCHEMBL7195638 0.73 HRH3 (0.51)
SCHEMBL4710730 0.67 DPP4 (0.46)
SCHEMBL4709983 0.67 DPP4 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231670-A2 PROCESS FOR THE PREPARATION OF 2-(PRIMARY/SECONDARY AMINO)HYDROCARBYL)- CARBAMOYL-7-OXO-2,6-DIAZA-BICYCLOÝ3.2.0.¨HEPTANE-6-SULFONIC ACID DERIVATIVES Basilea Pharmaceutica AG (CH) 2010-09-29 EP disclosed
WO-2009071638-A2 PROCESS FOR THE PREPARATION OF 2-(PRIMARY/SECONDARY AMINO)HYDROCARBYL)- CARBAMOYL-7-OXO-2,6-DIAZA-BICYCLO[3.2.0.]HEPTANE-6-SULFONIC ACID DERIVATIVES BASILEA PHARMACEUTICA AG (CH) 2009-06-11 WO disclosed