Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FHIT | P49789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1687128 | 1.00 | FHIT (0.30) | FHIT | |
| SCHEMBL5135067 | 1.00 | FHIT (0.30) | FHIT | |
| SCHEMBL5135065 | 1.00 | FHIT (0.30) | FHIT | |
| SCHEMBL3668079 | 0.79 | L3MBTL1 (0.33) | — | |
| SCHEMBL3608557 | 0.79 | L3MBTL1 (0.33) | — | |
| SCHEMBL2216944 | 0.70 | KDM4E (0.40) | — | |
| SCHEMBL7195638 | 0.68 | HRH3 (0.51) | — | |
| SCHEMBL7197551 | 0.66 | ROCK2 (0.38) | — | |
| SCHEMBL14489745 | 0.66 | DDB1 (0.32) | — | |
| SCHEMBL1686784 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1965798-A2 | USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS | Basilea Pharmaceutica AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007065288-A2 | USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2007-06-14 | — | — | WO | disclosed |