Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671847 | 0.84 | ACE2 (0.45) | PKMACE2EPHX2KLF10 | |
| SCHEMBL3676253 | 0.81 | PKM (0.46) | PKMACE2EPHX2KLF10 | |
| SCHEMBL3668232 | 0.81 | ACE2 (0.43) | PKMACE2EPHX2KLF10 | |
| SCHEMBL3738996 | 0.79 | CES2 (0.35) | EPHX2 | |
| SCHEMBL3669475 | 0.78 | ACE2 (0.43) | PKMACE2EPHX2KLF10 | |
| SCHEMBL3671501 | 0.78 | ACE2 (0.40) | PKMACE2EPHX2ELANE | |
| SCHEMBL3676655 | 0.78 | ALDH1A1 (0.43) | PKMACE2 | |
| SCHEMBL3677422 | 0.78 | ACE2 (0.40) | PKMACE2EPHX2KLF10ELANE | |
| SCHEMBL23071421 | 0.77 | SIRT1 (0.39) | — | |
| SCHEMBL8478122 | 0.77 | ACE2 (0.46) | PKMACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | claimed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | claimed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | claimed |
| CN-1942424-A | Novel photoinitiators | CIBA SC HOLDING AG (CH) | 2007-04-04 | — | — | CN | claimed |
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | claimed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | claimed |
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| CN-100548955-C | photoinitiator | CIBA SC HOLDING AG (CH) | 2009-10-14 | — | — | CN | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| CN-1942424-A | Novel photoinitiators | CIBA SC HOLDING AG (CH) | 2007-04-04 | — | — | CN | disclosed |
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |