SCHEMBL3668375

SCHEMBL3668375

O=C(O)c1cccc2c1c(=O)oc(=O)c1ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.51
PARP1 P09874 1/20 0.51
NR4A1 P22736 1/20 0.47
NR4A2 P43354 1/20 0.47
NR4A3 Q92570 1/20 0.47
ALDH1A1 P00352 4/20 0.46
GLA P06280 2/20 0.46
ALOX15 P16050 1/20 0.43
HPGD P15428 2/20 0.43
LMNA P02545 1/20 0.43
TYMS P04818 1/20 0.42
CDC25B P30305 1/20 0.42
KDM4E B2RXH2 3/20 0.42
GAA P10253 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
PBRM1 Q86U86 1/20 0.41
MAOB P27338 2/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9521993 0.93 GPR35 (0.47) GPR35PARP1NR4A1NR4A2NR4A3
SCHEMBL761372 0.93 PARP1 (0.53) GPR35PARP1NR4A1NR4A2NR4A3
SCHEMBL2804188 0.88 ALDH1A1 (0.51) GPR35PARP1NR4A1NR4A2NR4A3
SCHEMBL2876805 0.81 NR4A1 (0.61) GPR35PARP1NR4A1NR4A2NR4A3
SCHEMBL28539627 0.81 NR4A1 (0.61) GPR35PARP1NR4A1NR4A2NR4A3
SCHEMBL8568141 0.78 ALDH1A1 (0.46) GPR35PARP1NR4A1NR4A2NR4A3
SCHEMBL11271306 0.76 CYP1A2 (0.52) GPR35PARP1ALDH1A1GLAALOX15
SCHEMBL10683604 0.75 TTR (0.55) GPR35PARP1ALDH1A1GLAHPGD
SCHEMBL30966887 0.74 ALDH1A1 (0.58) GPR35ALDH1A1GLAALOX15HPGD
SCHEMBL257 0.74 ALDH1A1 (0.58) GPR35ALDH1A1GLAALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8449200-B2 Resin composition for sliding member and rolling bearing NTN CORPORATION (JP) 2013-05-28 US disclosed
US-8182155-B2 Lubricating grease and lubricating grease-enclosed roller bearing NTN CORPORATION (JP) 2012-05-22 US disclosed
US-20100142872-A1 RESIN COMPOSITION FOR SLIDING MEMBER AND ROLLING BEARING NTN CORPORATION (JP) 2010-06-10 US disclosed
EP-2157135-A1 RESIN COMPOSITION FOR SLIDE MEMBER AND ROLLER BEARING NTN Corporation (JP) 2010-02-24 EP disclosed
US-20090277666-A1 HEAT-RESISTANT RESIN VARNISH, HEAT-RESISTANT RESIN FILMS, HEAT-RESISTANT RESIN COMPOSITES, AND INSULATED WIRE SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2009-11-12 US disclosed
US-20090232432-A1 Lubricating grease and lubricating grease-enclosed roller bearing NTN CORPORATION (JP) 2009-09-17 US disclosed
EP-1956072-A1 LUBRICATING GREASE AND LUBRICATING-GREASE-FILLED ROLLER BEARING NTN CORPORATION (JP) 2008-08-13 EP disclosed
US-5840802-A HEAT RESISTANCE AND IMPACT STRENGTH FOR THERMOPLASTIC RESINS GENERAL ELECTRIC COMPANY (US) 1998-11-24 US disclosed
US-5306785-A Molding materials GENERAL ELECTRIC COMPANY (US) 1994-04-26 US disclosed
EP-0586181-A2 Thermoplastic polyester elastomer resin compositions GE PLASTICS JAPAN LIMITED (JP) 1994-03-09 EP disclosed
EP-0537014-A2 Dual graft stage and thermally stabilized polyorganisiloxane/polyvinyl-based graft copolymers and thermoplastic compositions containing the same GENERAL ELECTRIC COMPANY (US) 1993-04-14 EP disclosed
EP-0020773-B1 LIGHT-SENSITIVE POLYMER COMPOSITION Hitachi, Ltd. (JP) 1984-08-08 EP disclosed
US-4321319-A Photosensitive compositions containing polyamides acid with photosensitive groups HITACHI, LTD. (JP) 1982-03-23 US disclosed
EP-0020773-A1 LIGHT-SENSITIVE POLYMER COMPOSITION Hitachi, Ltd. (JP) 1981-01-07 EP disclosed
US-4129678-A POLYIMIDE, POLYAMIDEIMIDE OR POLYESTERIMIDE LAYER AND POLYVINYL FORMAL OR EPOXY RESIN LAYER HITACHI, LTD. (JP) 1978-12-12 US disclosed
US-4058503-A FROM AN ANHYDRIDE AND A DIHYDRAZIDE BRIDGESTONE TIRE COMPANY LIMITED (JA) 1977-11-15 US disclosed
US-3960980-A Method of producing elastomer resins BRIDGESTONE TIRE COMPANY LIMITED (JA) 1976-06-01 US disclosed