Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3672197 | 0.82 | MEN1 (0.33) | NISCHTSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL618964 | 0.81 | KDM4E (0.31) | — | |
| Hydrochloric Acid SCHEMBL346593 | 0.77 | ADRA2A (0.34) | NISCHADRA2AADRA2BADRA2CL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8762954 | 0.75 | CA4 (0.30) | — | |
| Hydrochloric Acid SCHEMBL15122062 | 0.70 | BACE1 (0.36) | CYP1A2CYP2C19 | |
| SCHEMBL3752527 | 0.70 | SLC6A2 (0.35) | NISCHADRA2AADRA2BADRA2CSLC6A2 | |
| Hydrochloric Acid SCHEMBL5729183 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL7931040 | 0.64 | TSHR (0.40) | SLC6A2SLC6A3TSHRMEN1KMT2A | |
| SCHEMBL4575432 | 0.62 | P2RX3 (0.58) | NISCHADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL31257131 | 0.62 | CA1 (0.60) | ADRA2BCYP1A2CYP2C19TSHRP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225251-B1 | TRANSITION METAL COMPLEXES, CATALYSTS COMPOSITION CONTAINING THE SAME, AND PROCESS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS USING THE SAME | SABIC SK NEXLENE COMPANY PTE LTD (SG) | 2015-12-23 | — | — | EP | disclosed |
| US-8344081-B2 | Transition metal complexes, catalysts composition containing the same, and process for preparing ethylene homopolymers or copolymers of ethylene and alpha-olefins using the same | SK INNOVATION CO., LTD. (KR) | 2013-01-01 | — | — | US | disclosed |
| US-20100298512-A1 | TRANSITION METAL COMPLEXES, CATALYSTS COMPOSITION CONTAINING THE SAME, AND PROCESS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS USING THE SAME | SK ENERGY CO., LTD. (KR) | 2010-11-25 | — | — | US | disclosed |
| EP-2225251-A1 | TRANSITION METAL COMPLEXES, CATALYSTS COMPOSITION CONTAINING THE SAME, AND PROCESS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS USING THE SAME | SK Energy Co., Ltd. (KR) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009084805-A1 | TRANSITION METAL COMPLEXES, CATALYSTS COMPOSITION CONTAINING THE SAME, AND PROCESS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS USING THE SAME | SK ENERGY CO., LTD. (KR) | 2009-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298512-A1 | TRANSITION METAL COMPLEXES, CATALYSTS COMPOSITION CONTAINING THE SAME, AND PROCESS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS USING THE SAME | MCM4, ESR1, SEM1 | SLC6A2 4134/4885SLC6A3 4335/4885NISCH 2559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.