Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 7/20 | 0.36 |
| ▸ | ITK | Q08881 | 5/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2608182 | 0.89 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL15373709 | 0.83 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL784556 | 0.83 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL784557 | 0.81 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL784470 | 0.80 | ZDHHC20 (0.40) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL1278058 | 0.80 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL4455953 | 0.79 | ZDHHC20 (0.48) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL26478811 | 0.79 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL21300154 | 0.79 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL16803244 | 0.79 | TSHR (0.50) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | UNIVERSITEIT UTRECHT (NL) | 2012-01-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | LCT, LDHA, LDHB | ZDHHC20 2972/4885ZDHHC2 3582/4885TSHR 4451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.