Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18203203 | 0.95 | ALDH1A1 (0.35) | CYP2D6CYP2C19GMNNUSP2CYP1A2 | |
| SCHEMBL18203204 | 0.95 | ALDH1A1 (0.35) | CYP2D6CYP2C19GMNNUSP2CYP1A2 | |
| Butane SCHEMBL2917528 | 0.79 | TSHR (0.33) | CYP2D6CYP2C19GMNNUSP2CYP1A2 | |
| SCHEMBL9718363 | 0.76 | ALDH1A1 (0.35) | CYP2D6CYP2C19GMNNUSP2CYP1A2 | |
| SCHEMBL9718359 | 0.76 | ALDH1A1 (0.35) | CYP2D6CYP2C19GMNNUSP2CYP1A2 | |
| SCHEMBL18187549 | 0.74 | ALDH1A1 (0.39) | CYP2D6CYP2C19GMNNUSP2CYP1A2 | |
| SCHEMBL10702570 | 0.73 | ALDH1A1 (0.37) | CYP3A4RECQLBLMHSD17B10ALDH1A1 | |
| SCHEMBL11124088 | 0.71 | ALDH1A1 (0.32) | CYP2D6CYP2C19GMNNUSP2CYP1A2 | |
| SCHEMBL11124099 | 0.71 | ALDH1A1 (0.32) | CYP2D6CYP2C19GMNNUSP2CYP1A2 | |
| SCHEMBL11749518 | 0.70 | ALDH1A1 (0.34) | CYP3A4RECQLBLMHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951750-B2 | Malonate decarboxylases for industrial applications | BASF SE (DE) | 2015-02-10 | — | — | US | disclosed |
| US-20100311037-A1 | MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | BASF SE (DE) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311037-A1 | MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | ME1, AMD1, GMDS | CYP2D6 529/4885CYP2C19 2054/4885GMNN 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.