Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669239 | 0.89 | ALDH1A1 (0.46) | ALDH1A1GPBAR1PTGS1PTGS2TACR1 | |
| SCHEMBL3668571 | 0.78 | GPBAR1 (0.52) | GPBAR1TACR1 | |
| SCHEMBL3671696 | 0.77 | NAMPT (0.51) | ALDH1A1PTGS1PTGS2NAMPTRORC | |
| SCHEMBL3671698 | 0.74 | NAMPT (0.53) | ALDH1A1PTGS1PTGS2NAMPTRORC | |
| SCHEMBL29642739 | 0.71 | ALDH1A1 (0.62) | ALDH1A1NAMPTHPGDHTT | |
| SCHEMBL1949604 | 0.71 | PTGDR2 (0.60) | NAMPTPTGER2 | |
| SCHEMBL3672556 | 0.70 | TACR1 (0.55) | GPBAR1TACR1 | |
| SCHEMBL3668574 | 0.68 | GPBAR1 (0.52) | GPBAR1TACR1 | |
| SCHEMBL3674357 | 0.68 | MTOR (0.56) | TACR1 | |
| SCHEMBL3665166 | 0.68 | TACR1 (0.47) | GPBAR1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | claimed |