Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 12/20 | 0.52 |
| ▸ | TACR1 | P25103 | 7/20 | 0.47 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3668574 | 0.90 | GPBAR1 (0.52) | GPBAR1TACR1TRPV4 | |
| SCHEMBL3672556 | 0.90 | TACR1 (0.55) | GPBAR1TACR1 | |
| SCHEMBL3672557 | 0.79 | TACR1 (0.55) | GPBAR1TACR1 | |
| SCHEMBL3669238 | 0.78 | ALDH1A1 (0.47) | GPBAR1TACR1 | |
| SCHEMBL3670285 | 0.77 | TRPV4 (0.43) | GPBAR1TACR1TRPV4 | |
| SCHEMBL3665166 | 0.76 | TACR1 (0.47) | GPBAR1TACR1 | |
| SCHEMBL3674357 | 0.76 | MTOR (0.56) | TACR1 | |
| SCHEMBL3669056 | 0.75 | TACR1 (0.43) | GPBAR1TACR1 | |
| SCHEMBL3670286 | 0.74 | HSD17B1 (0.45) | GPBAR1TACR1TRPV4 | |
| SCHEMBL3671389 | 0.73 | TACR1 (0.43) | GPBAR1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | claimed |