SCHEMBL366924

SCHEMBL366924

NC(=O)c1ccc(C(=O)n2c3ccc2c(Cl)c3)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 5/20 0.40
PARP2 Q9UGN5 3/20 0.40
BCAT2 O15382 1/20 0.39
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HSD17B10 Q99714 2/20 0.38
KDM4E B2RXH2 1/20 0.38
BRD4 O60885 1/20 0.38
BRPF1 P55201 1/20 0.38
ROCK2 O75116 1/20 0.37
PIM1 P11309 1/20 0.37
PIM3 Q86V86 1/20 0.37
PTGS2 P35354 2/20 0.36
MKNK1 Q9BUB5 1/20 0.36
MKNK2 Q9HBH9 1/20 0.36
MAP4K4 O95819 1/20 0.36
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
KMT2A Q03164 2/20 0.35
PARP15 Q460N3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29120355 0.97 PARP1 (0.39) PARP1PARP2BCAT2ALDH1A1SMN1; SMN2
SCHEMBL8970415 0.86 PARP1 (0.47) PARP1PARP2ALDH1A1SMN1; SMN2HSD17B10
SCHEMBL9741290 0.81 SMN1; SMN2 (0.41) PARP1PARP2ALDH1A1SMN1; SMN2HSD17B10
SCHEMBL11498522 0.80 BCAT2 (0.41) PARP1PARP2BCAT2ALDH1A1SMN1; SMN2
SCHEMBL28393844 0.77 ALDH1A1 (0.39) PARP1PARP2ALDH1A1SMN1; SMN2HSD17B10
SCHEMBL174536 0.77 PARP10 (0.46) PARP1PARP2ALDH1A1SMN1; SMN2HSD17B10
SCHEMBL3307901 0.76 BCAT2 (0.41) PARP1PARP2BCAT2ALDH1A1SMN1; SMN2
SCHEMBL11498322 0.76 PARP1 (0.47) PARP1ALDH1A1SMN1; SMN2KMT2AMAPT
Urea SCHEMBL11673195 0.75 PARP10 (0.45) PARP1PARP2ALDH1A1SMN1; SMN2HSD17B10
SCHEMBL28344986 0.75 PARP10 (0.45) PARP1PARP2ALDH1A1SMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100559526-C Separator for electrochemical element MITSUBISHI PAPER MILLS LTD (JP) 2009-11-11 CN claimed
CN-1942983-A Separator for electrochemical element MITSUBISHI PAPER MILLS LTD (JP) 2007-04-04 CN claimed
EP-0870795-B1 Composite film comprising low-dielectric resin and para-oriented aromatic polyamide SUMITOMO CHEMICAL CO (JP) 2007-01-31 EP claimed
EP-0762437-B1 Electrical circuit protection devices comprising PTC conductive liquid crystal polymer compositions EATON CORP (US) 2003-01-22 EP claimed
US-6121171-A THE CONTINUOUS PHASE OF PARA-ORIENTED AROMATIC POLYAMIDE HAS A LAMINATED STRUCTURE OF FIBRILS WHICH HAVE DIAMETERS OF NOT MORE THAN 1 MU.M AND ARE ARRANGED IN THE FORM OF A PLANAR NETWORK OR A NONWOVEN FABRIC SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2000-09-19 US claimed
EP-0870795-A1 Composite film comprising low-dielectric resin and para-oriented aromatic polyamide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-14 EP claimed
EP-0762437-A2 Electrical circuit protection devices comprising PTC conductive liquid crystal polymer compositions EATON CORPORATION (US) 1997-03-12 EP claimed
US-4112016-A AND MELAMINE-FORMALDEHYDE RESIN, GUANIDINE MAGNESIUM PHOSPHATE OR GUANIDINE PHOSPHATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-09-05 US claimed
CN-109935880-B Nonaqueous electrolyte secondary battery 住友化学株式会社 2024-02-06 CN disclosed
CN-117335098-A Laminated separator for nonaqueous electrolyte secondary battery 住友化学株式会社 2024-01-02 CN disclosed
CN-117175142-A Separator for nonaqueous electrolyte secondary battery 住友化学株式会社 2023-12-05 CN disclosed
CN-117134071-A Laminated separator for nonaqueous electrolyte secondary battery 住友化学株式会社 2023-11-28 CN disclosed
CN-109935890-B Nonaqueous electrolyte secondary battery 住友化学株式会社 2023-10-13 CN disclosed
CN-116706433-A Separator for nonaqueous electrolyte secondary battery, member for nonaqueous electrolyte secondary battery, and nonaqueous electrolyte secondary battery 住友化学株式会社 2023-09-05 CN disclosed
EP-0153629-A1 A process for producing reinforced polyurethane tires LIM INTERNATIONAL S.A. (LU) 1985-09-04 EP disclosed
US-4519432-A LOW HYSTERESIS LIM INTERNATIONAL S.A. (LU) 1985-05-28 US disclosed
US-4297479-A HIGH VISCOSITY, SPINNABLE HOMO- OR COPOLYMER FROM P-DIAMINOBENZENE AND TEREPHTHALOYL CHLORIDE RHONE-POULENC-TEXTILE (FR) 1981-10-27 US disclosed
US-4297478-A HIGH VISCOSITY SPINNABLE HOMO- OR COPOLYMERS FROM P-DIAMINOBENZENE AND TEREPHTHALOYL CHLORIDE RHONE-POULENC-TEXTILE (FR) 1981-10-27 US disclosed
US-RE30352-E AMIDE OR UREA CONTAINING SALT, SULFURIC ACID, HYDROFLUORIC ACID, OR HALO- OR METHANESULFONIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-29 US disclosed
US-4112016-A AND MELAMINE-FORMALDEHYDE RESIN, GUANIDINE MAGNESIUM PHOSPHATE OR GUANIDINE PHOSPHATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-09-05 US disclosed