SCHEMBL3669290

SCHEMBL3669290

C=Cc1ccccc1CC(C)C=C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
ADRB2 P07550 3/20 0.31
ADRB1 P08588 3/20 0.31
LMNA P02545 2/20 0.31
HTR1A P08908 1/20 0.31
ADRB3 P13945 1/20 0.31
ADRA2C P18825 1/20 0.31
SLC6A2 P23975 1/20 0.31
BDKRB2 P30411 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31
HTR2B P41595 1/20 0.31
KCNH2 Q12809 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30641415 0.84 GABRA1 (0.47) ALDH1A1GABRA1GABRB2ADRB2ADRB1
SCHEMBL535990 0.84 GABRA1 (0.47) ALDH1A1GABRA1GABRB2ADRB2ADRB1
SCHEMBL6025866 0.82 ALDH1A1 (0.39) ALDH1A1GABRA1GABRB2ADRB2ADRB1
SCHEMBL28579563 0.81 SLC6A2 (0.45) ALDH1A1ADRB1HTR1ASLC6A2SLC6A4
SCHEMBL6289164 0.81 ALDH1A1 (0.38) ALDH1A1GABRA1GABRB2ADRB2ADRB1
SCHEMBL810093 0.81 ALDH1A1 (0.42) ALDH1A1GABRA1GABRB2ADRB2ADRB1
SCHEMBL5033204 0.79 ALDH1A1 (0.36) ALDH1A1GABRA1GABRB2ADRB2ADRB1
SCHEMBL8848613 0.78 TAAR1 (0.41) ALDH1A1SLC6A2SLC6A4KCNH2CYP2D6
Bromide SCHEMBL5671803 0.78 ALDH1A1 (0.39) ALDH1A1GABRA1GABRB2ADRB2ADRB1
Hydrochloric Acid SCHEMBL3669415 0.78 ALDH1A1 (0.39) ALDH1A1GABRA1GABRB2ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US claimed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US claimed
US-8461271-B2 Graft copolymer, thermoplastic resin composition comprising the graft copolymer, and those production method IDEMITSU KOSAN CO., LTD. (JP) 2013-06-11 US disclosed
EP-1408080-B1 POLYOLEFIN RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2012-12-26 EP disclosed
US-20100076146-A1 GRAFT COPOLYMER, THERMOPLASTIC RESIN COMPOSITION COMPRISING THE GRAFT COPOLYMER, AND THOSE PRODUCTION METHOD IDEMITSU KOSAN CO., LTD. (JP) 2010-03-25 US disclosed
US-7531605-B2 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU KOSAN CO., LTD. (JP) 2009-05-12 US disclosed
EP-1375538-B1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU KOSAN CO (JP) 2008-01-09 EP disclosed
US-7193013-B2 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2007-03-20 US disclosed
US-7189788-B2 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2007-03-13 US disclosed
EP-1367093-B1 POLYOLEFIN RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2005-12-14 EP disclosed
US-20040176520-A1 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2004-09-09 US disclosed
EP-0686649-B1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN CO (JP) 2000-08-02 EP disclosed
US-5670580-A POLYMERS FOR ANTISTATIC AGENTS, ADHESIVES AND FIREPROOFING IDEMITSU KOSAN CO., LTD. (JP) 1997-09-23 US disclosed
EP-0559108-B1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN CO (JP) 1997-05-28 EP disclosed
US-5608009-A OLEFIN-DIOLEFIN GRAFT POLYMER IDEMITSU KOSAN CO., LTD. (JP) 1997-03-04 US disclosed
EP-0686649-A1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-12-13 EP disclosed
EP-0667359-A1 OLEFIN COPOLYMERS AND PROCESS FOR PRODUCING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-08-16 EP disclosed
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US disclosed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US disclosed
EP-0559108-A1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-08 EP disclosed