SCHEMBL3669795

SCHEMBL3669795

CC(C)(C)C(OC(N)=O)C1COCc2cc(N)cnc21

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.32
CSNK2A1 P68400 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28345899 0.61 ATM (0.32)
SCHEMBL14830518 0.61 ATM (0.32)
SCHEMBL28345897 0.61 ATM (0.32)
SCHEMBL17076623 0.58 ALOX5 (0.35) CSNK2A2CSNK2A1
SCHEMBL28913839 0.57 CSNK2A2 (0.34) CSNK2A2CSNK2A1
SCHEMBL21963311 0.56 CSNK2A2 (0.33) CSNK2A2CSNK2A1
SCHEMBL3630902 0.56 LMNA (0.32) CSNK2A2CSNK2A1
SCHEMBL21465832 0.55 NNMT (0.33)
SCHEMBL3718804 0.55 CHRM4 (0.34)
SCHEMBL25147811 0.55 NR1H2 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2139898-A1 COMPOUNDS Glaxo Group Limited (GB) 2010-01-06 EP disclosed
WO-2008128961-A1 COMPOUNDS GLAXO GROUP LIMITED (GB) 2008-10-30 WO disclosed