Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008901 | 0.96 | MEN1 (0.46) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| Bromide SCHEMBL28138957 | 0.94 | KMT2A (0.44) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL1307189 | 0.94 | MEN1 (0.44) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL17983446 | 0.92 | ENPP3 (0.36) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL13963161 | 0.89 | MAPT (0.41) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL17066733 | 0.86 | ENPP3 (0.46) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL8932214 | 0.84 | NPC1 (0.49) | RAB9ATSHRNPC1 | |
| Nitric Acid SCHEMBL28186561 | 0.84 | ALDH1A1 (0.43) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL28136880 | 0.84 | TP53 (0.41) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL8250696 | 0.83 | METAP2 (0.44) | MEN1KMT2AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162441-A2 | 1,(3,)5-SUBSTITUTED IMIDAZOLES, THEIR USE IN THE TREATMENT OF HYPERTENSION AND METHODS FOR THEIR PREPARATION | Eldrug S.A. (GR) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008142576-A2 | 1,(3,)5-SUBSTITUTED IMIDAZOLES, THEIR USE IN THE TREATMENT OF HYPERTENSION AND METHODS FOR THEIR PREPARATION | ELDRUG S.A. (GR) | 2008-11-27 | — | — | WO | disclosed |
| EP-0652869-A1 | IMIDAZOLE ETHERS HAVING A II ANTAGONIST ACTIVITY. | LUSO FARMACO INST (IT) | 1995-05-17 | — | — | EP | disclosed |