Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 5/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 6/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 6/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670680 | 1.00 | MGLL (0.43) | MGLLSLC6A9CNR1CNR2CACNA2D1 | |
| SCHEMBL1500614 | 0.83 | MGLL (0.43) | MGLLCNR1CNR2SLC6A2SLC6A4 | |
| SCHEMBL1500612 | 0.83 | MGLL (0.43) | MGLLCNR1CNR2SLC6A2SLC6A4 | |
| SCHEMBL14769296 | 0.77 | SLC6A9 (0.52) | SLC6A9CACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL1500702 | 0.77 | MGLL (0.42) | MGLLCNR1CNR2SLC6A2SLC6A4 | |
| SCHEMBL1500704 | 0.77 | MGLL (0.42) | MGLLCNR1CNR2SLC6A2SLC6A4 | |
| SCHEMBL4683968 | 0.75 | CNR1 (0.37) | MGLLCNR1CNR2KCNH2 | |
| SCHEMBL4479263 | 0.74 | MGLL (0.38) | MGLLSLC6A9CNR1CNR2HRH1 | |
| SCHEMBL4479268 | 0.74 | MGLL (0.38) | MGLLSLC6A9CNR1CNR2HRH1 | |
| SCHEMBL3673122 | 0.74 | MGLL (0.41) | MGLLSLC6A9CNR1CNR2CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081642-A1 | CB-1 RECEPTOR MODULATOR PHARMACEUTICAL FORMULATIONS | MERCK SHARP & DOHME CORP. | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081642-A1 | CB-1 RECEPTOR MODULATOR PHARMACEUTICAL FORMULATIONS | CNR1, CNR2, GPBAR1 | MGLL 625/4885SLC6A9 2355/4885CNR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.