Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 9/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672078 | 0.86 | ACHE (0.44) | ACHESMN1; SMN2 | |
| SCHEMBL3674783 | 0.82 | LSS (0.48) | PYCR1SMN1; SMN2 | |
| SCHEMBL11706284 | 0.80 | ACHE (0.47) | SIGMAR1TMEM97PYCR1ACHEBCHE | |
| Hydrochloric Acid SCHEMBL2457698 | 0.79 | ACHE (0.46) | SIGMAR1TMEM97PYCR1ACHEBCHE | |
| SCHEMBL4422777 | 0.78 | RXRA (0.46) | PYCR1SMN1; SMN2 | |
| SCHEMBL154857 | 0.76 | CYP4A11 (0.50) | — | |
| SCHEMBL5776546 | 0.76 | CYP4A11 (0.57) | SIGMAR1ACHEBCHESMN1; SMN2 | |
| SCHEMBL480503 | 0.76 | EPHX2 (0.49) | THRATHRBSMN1; SMN2 | |
| SCHEMBL4561898 | 0.76 | EGFR (0.40) | — | |
| SCHEMBL11714658 | 0.75 | ACHE (0.43) | SIGMAR1TMEM97PYCR1ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |