Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367102 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDKMT2ATDP1 | |
| SCHEMBL365839 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDKMT2ATDP1 | |
| SCHEMBL366971 | 0.75 | MAPT (0.48) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL365618 | 0.75 | L3MBTL1 (0.39) | ALDH1A1MAPTKMT2ATDP1SLC6A2 | |
| SCHEMBL366408 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDKMT2ATDP1 | |
| SCHEMBL366763 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDKMT2ATDP1SLC6A3 | |
| SCHEMBL365432 | 0.73 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDKMT2ALMNA | |
| SCHEMBL365411 | 0.73 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2ATDP1KDM4E | |
| SCHEMBL367492 | 0.72 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDKMT2ALMNA | |
| SCHEMBL364887 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |