Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364734 | 0.92 | LMNA (0.40) | L3MBTL1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL365200 | 0.92 | TP53 (0.40) | L3MBTL1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL364749 | 0.91 | ESR1 (0.38) | L3MBTL1NPC1KMT2ATDP1ALDH1A1 | |
| SCHEMBL367137 | 0.90 | ALOX5 (0.40) | KMT2ATDP1ALDH1A1KDM4EMEN1 | |
| SCHEMBL364902 | 0.90 | ALDH1A1 (0.40) | L3MBTL1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL365579 | 0.89 | MAOB (0.38) | L3MBTL1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL365359 | 0.87 | ALDH1A1 (0.47) | L3MBTL1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL366275 | 0.86 | ALDH1A1 (0.36) | L3MBTL1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL365513 | 0.86 | NPC1 (0.40) | L3MBTL1NPC1KMT2AALDH1A1MAPT | |
| SCHEMBL365979 | 0.86 | ALDH1A1 (0.36) | L3MBTL1KMT2ATDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |